Computational Fluid Dynamic Analysis of Intracranial Aneurysmal Bleb Formation
نویسندگان
چکیده
منابع مشابه
Computational fluid dynamic analysis of intracranial aneurysmal bleb formation.
BACKGROUND The management of unruptured aneurysms is controversial, with the decision to treat influenced by aneurysm characteristics including size and morphology. Aneurysmal bleb formation is thought to be associated with an increased risk of rupture. OBJECTIVE To correlate computational fluid dynamic (CFD) indices with bleb formation. METHODS Anatomic models were constructed from 3-dimen...
متن کاملHemodynamics and bleb formation in intracranial aneurysms.
BACKGROUND AND PURPOSE Intracranial aneurysms with irregular shapes and blebs or secondary outpouchings have been correlated with increased rupture risk. The purpose of this study was to investigate possible associations between the local hemodynamics and the formation of blebs in cerebral aneurysms. MATERIALS AND METHODS Computational models of 20 cerebral aneurysms harboring 30 well-defined...
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Blebbing occurs when the cytoskeleton detaches from the cell membrane, resulting in the pressure-driven flow of cytosol towards the area of detachment and the local expansion of the cell membrane. Recent interest has focused on cells that use blebbing for migrating through 3D fibrous matrices. In particular, metastatic cancer cells have been shown to use blebs for motility. A dynamic computatio...
متن کاملComputational fluid dynamics modeling of intracranial aneurysms: effects of parent artery segmentation on intra-aneurysmal hemodynamics.
PURPOSE The purpose of this study is to show the influence of the upstream parent artery geometry on intraaneurysmal hemodynamics of cerebral aneurysms. METHODS Patient-specific models of 4 cerebral aneurysms (1 posterior communicating artery [PcomA], 2 middle cerebral artery [MCA], and 1 anterior communicating artery [AcomA]) were constructed from 3D rotational angiography images. Two geomet...
متن کاملIntracranial aneurysm neck size overestimation with 3D rotational angiography: the impact on intra-aneurysmal hemodynamics simulated with computational fluid dynamics.
BACKGROUND AND PURPOSE 3DRA is considered the reference standard for the assessment of intracranial aneurysm morphology. However, it has been shown that 3DRA may overestimate neck size compared with 2D DSA. The purpose of this study was to determine the impact of neck size overestimation with 3DRA on intra-aneurysmal hemodynamics. MATERIALS AND METHODS In a series of 20 patients, 20 intracran...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2013
ISSN: 0148-396X,1524-4040
DOI: 10.1227/neu.0000000000000137